The integration of proteomic technologies into clinical practice indeed holds significant promise for revolutionizing disease diagnosis, prognosis, and treatment. By delving into the intricate world of proteins and their modifications, researchers aim to unravel the complexities underlying various diseases. The advanced proteomic technologies also offer unprecedented opportunities to investigate the interplay between genomic, transcriptomic, and proteomic alterations. By employing these technologies to investigate tumors, we have gained invaluable insights into cancer biology, particularly pertaining to protein modifications such as glycosylation.