New-generation Optical Endomicroscopy Technologies towards Histological Imaging of Biological Tissues in vivo

活动信息

  • 开始时间:网上投稿
  • 活动地点:新一代光学内窥成像
  • 主讲人:张宾

活动简介

[报告简介]This presentation will focus on our recent progresses on developing high-resolution biophotonic imaging technologies, particularly the second-generation optical coherence tomography (OCT) endoscopy and multiphoton endomicroscopy. These technologies have shown promising translational potential for direct visualization of tissue microanatomiesin vivo,in situand in real time at a resolution from morphological to cellular, subcellular and ECM level, which approaches or at standard histopathology but without the need for tissue removal, staining or processing. The physics principles, engineering challenges and solutions will be briefly discussed, including the development of advanced lasers, MEMS technology, custom optical fiber, and ultracompact, high-performance imaging optics. Representative applications of these optical technologies will be presented, including cancer detection, small airway pathophysiology imaging, preterm birth risk assessment, and intra-operative guidance for neurosurgery. Other potential applications towards basic research such as functional neuroimaging on freely walking animals will also be discussed.

[报告人简介]Dr. Xingde Li received his PhD degree in Physics and Astronomy from the University of Pennsylvania in 1998. He has published about 100 peer-reviewed journal papers, with a total citation ~13,500 and an H-index ~47 (Google Scholar). Several of his patents have been licensed and converted to commercial products. He served as the chair of Emerging Technologies Committee of IEEE-EMBS (2006-2010). He has chaired many conferences such as the recent OSA Biomedical Optics Topical Meetings 2010-2014. He serves on serval grant review panels for various funding agencies including NIH, NSF, Singapore and EU. He has been a topical editor or associate editor for several international journals includingthe Journal of Biomedical Optics(SPIE),Biomedical Optics Express(OSA),the IEEE Transactions on Biomedical Engineering,Light: Science and Applications(Nature Publishing Group and CIOMP) etc. He was elected to China National 1000 Talents Plan (B) in 2014, and is a Fellow of OSA, SPIE, and AIMBE.

主讲人介绍

[报告简介]This presentation willfocus on our recent progresses on developing high-resolution biophotonicimaging technologies, particularly the second-generation optical coherencetomography (OCT) endoscopy and multiphoton endomicroscopy. These technologies have shown promising translationalpotential for direct visualization of tissue microanatomies